产品货号：
Z12142
中文名称：
ATP2C1抗体
英文名称：
Anti-ATP2C1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ATP2C1 Antibody |
| 指标别名 | ATP dependent Ca(2+) pump PMR1;ATP2C1;ATP2C1A;ATPase 2C1;HHD;hSPCA1;KIAA1347;PMR1;PMR1L;SPCA1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | ATP2C1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | ATP2C1 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human ATP2C1.The immunogen is located within the last 50 amino acids of ATP2C1. |
| 计算分子量 | 101kDa |
| 成分 | ATP2C1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | ATP2C1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | ATP2C1,also known as secretory pathway Ca2+/Mn2+-ATPase (SPCA) 1,belongs to the family of P-type cation transport ATPases.This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of the calcium from the cytosol to the Golgi lumen.Defects in this gene cause Hailey-Hailey disease,an autosomal dominant disorder characterized by persistent blisters and erosions of the skin.Unlike the related protein ATP2C2,ATP2C1 is ubiquitously expressed and displays a lower maximal turnover rate for overall Ca2+-ATPase reaction and a higher apparent affinity for cytosolic Ca2+ activation of phosphorylation.Recent evidence suggests that ATP2C1 is a key regulator of insulin-like growth factor receptor (IGF1R) processing in tumor progression in basal breast cancers. |
| Uniprot ID | P98194 |
| 基因名全称 | ATPase,Ca++ transporting,type 2C,member 1 |
| 蛋白名全称 | ATPase,Ca++ transporting,type 2C,member 1 |
| 推荐稀释比 | ATP2C1 antibody can be used for detection of ATP2C1 by Western blot at 1μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in mouse samples;Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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